The Integrated Health and Social Services Center (CISSS) des Laurentides is among a list of 127 centers and units of research across the world participating in clinical trials to develop treatments for COVID-19.

The Clinical Research Unit of the CISSS des Laurentides, under the scientific direction of Dr. Yves Pesant, is carrying out these studies at the Saint-Jérôme Regional Hospital and, more recently, at the Saint-Eustache Hospital.

Dr. Sébastien Poulin, for his part, acts as principal investigator for all projects dealing with COVID-19. Clinical trials conducted at the CONCOR-1 project establishment: aims to determine the effectiveness of a plasma transfusion from patients recovered from COVID-19 to treat hospitalized patients suffering from this disease.

RESOLUTION project: aims to verify whether the drug LAU-7b can reduce the severity of coronavirus disease, prevent rapid progression to severe breathing difficulties and decrease the need for additional oxygen during illness.

OSCAR project: evaluates the effectiveness of the new drug Otilimab on the needs for supplemental oxygen in patients with COVID-19. In addition, this study also aims to counter the phenomenon called “cytokine storm” a complication of COVID-19 corresponding to an overreaction of the immune system that can lead to death.

Mr. Jean-Philippe Cotton, Deputy Chairman and CEO of the CISSS des Laurentides, stressed the importance of these clinical trials in the establishment: “In a situation of health crisis like the one we are currently experiencing, clinical research constitutes a key element in our fight against COVID-19. I am very proud that our Clinical Research Unit is contributing to international efforts to develop effective treatments for this disease. We can count on this committed team and all their partners, just like all the CISSS des Laurentides teams who have been doing exceptional work since the very beginning of the crisis.